| dc.description.abstract | To assess how relevant the flow of people between communities is, compared to vaccination and
type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community.
Methods. Using a SEIRV-SEI model for humans and vectors, we applied numerical simulations to the scenarios:
(1) migration from an endemic community to a disease-free host community, comparing the performance
of Haemagogus janthinomys and Aedes aegypti as vectors; (2) migration through a transit community located
on a migratory route, where the disease is endemic, to a disease-free one; and (3) effects of different vaccination
rates in the host community, considering the vaccination of migrants upon arrival.
Results. Results show no remarkable differences between scenarios 1 and 2. The type of vector and vaccination
coverage in the host community are more relevant for the occurrence of outbreaks than migration rates,
with H. janthinomys being more effective than A. aegypti.
Conclusions. With vaccination being more determinant for a potential outbreak than migration rates, vaccinating
migrants on arrival may be one of the most effective measures against yellow fever. Furthermore,
H. janthinomys is a more competent vector than A. aegypti at similar densities, but the presence of A. aegypti
is a warning to maintain vaccination above recommended levels | en |
